A mattress allergy cover can help keep dust, dander, and other household particles from collecting in your mattress, while some styles also block spills. The right choice depends on your mattress size and depth, whether you want a full zippered encasement or a fitted protector, and how you plan to wash it. These five options include both styles, with different coverage and care details to compare.
Quick Comparison
| Product | Style | Key details | Best for |
|---|---|---|---|
| AllerEase Maximum Waterproof Zippered Mattress Protector | Zippered encasement | Waterproof; queen and king mattresses up to 15 inches deep | Shoppers wanting a zippered cover with liquid protection |
| AllerEase Ultimate Cotton Top Waterproof Mattress Protector | Fitted protector | Cotton top; waterproof; temperature-balancing fabric technology | Those who prefer a cotton-top fitted style |
| HOSPITOLOGY PRODUCTS Mattress Encasement | Zippered encasement | Queen; fits 12- to 18-inch depths; waterproof on all six sides | Queen mattresses with a deeper profile |
| SureGuard Mattress Encasement | Zippered encasement | Queen; fits 13- to 16-inch depths; cotton terry top | Those who want a six-sided cover with a cotton surface |
| Utopia Bedding King Size Zippered Mattress Protector | Zippered encasement | King; fits mattresses up to 15 inches deep; waterproof | King-size beds needing all-around coverage |
Our Picks: Best Allergy Cover For Mattress reviews
AllerEase Maximum: A Waterproof Zippered Encasement
This AllerEase option is a zippered mattress encasement with a waterproof layer beneath its soft top fabric. Its enclosed design covers the mattress, while the waterproof backing helps protect it from spills and stains. It is a practical choice if you want an allergy-focused cover and liquid protection in one product.
Fit depends on the mattress size: the listed maximum depth is 12 inches for twin and full sizes, and 15 inches for queen and king sizes. Measure your mattress, including any pillow top, before ordering. The care instructions call for a hot machine wash with nonchlorine bleach when needed and a separate tumble dry on the lowest setting. The manufacturer advises removing it when dry and not ironing it.
Compared with the fitted AllerEase protector below, this model offers a zippered enclosure rather than a fitted-cover style. Its main tradeoff is that the listed depth limits may rule it out for thicker mattresses. The product description also specifies careful low-heat drying, so it may require more attention at laundry time.
Pros:
- Zippered encasement design
- Waterproof layer helps protect against spills and stains
- Queen and king sizes fit mattresses up to 15 inches deep
- Includes a lifetime warranty, according to the product description
Cons:
- Maximum fit depth varies by mattress size
- Drying instructions call for the lowest setting and prompt removal
Verdict: Choose this AllerEase encasement if you want a zippered cover with waterproof protection and your mattress falls within its stated depth limits.
AllerEase Ultimate: A Cotton-Top Fitted Protector
The AllerEase Ultimate is a full-size fitted mattress protector with a cotton top, waterproof design, and FlexFit technology. Unlike the zippered encasements in this roundup, it is a fitted protector, so check the product listing for its fit details before buying. The description says its fabric is designed to help prevent 99.9% of unhealthy household particles from collecting in the mattress.
Its temperature-balancing fabric is described as retaining heat when you are cold and releasing it when you are hot. That may appeal if you want a protector with a cotton surface and fabric designed for temperature comfort. It is also machine washable, and the product description lists a limited lifetime warranty.
This is the only pick here specifically described as having a cotton top and temperature-balancing technology. The tradeoff is that it is not presented as a zippered, six-sided encasement, so shoppers seeking a fully enclosed mattress cover should compare it with the other options instead.
Pros:
- Cotton-top surface
- Waterproof design
- Temperature-balancing fabric technology
- Machine washable, with a limited lifetime warranty listed
Cons:
- Fitted protector style rather than a zippered encasement
- Listed here in full size, so confirm the available size and fit before ordering
Verdict: This is a strong option to consider if you want a cotton-top fitted protector with waterproofing, rather than a zippered mattress enclosure.
HOSPITOLOGY PRODUCTS: A Deep-Fit Queen Encasement
This queen-size zippered encasement fits standard mattresses measuring 60 by 80 inches with depths from 12 to 18 inches. It provides a waterproof barrier on all six sides, making it a useful choice when you want to enclose the mattress rather than cover only its top and sides.
The cover uses extra-soft polyester knit fabric, paired with a breathable waterproof membrane. That combination is intended to provide a softer, cooler-feeling surface than a stiff cover. The product description also identifies it as bed bug and dust mite proof, and says it can help reduce common substances that reach the sleeper and disrupt respiratory function.
Its 18-inch maximum depth is the widest fit range among the queen encasements in this group. The main limitation is size: this listing is for queen mattresses, so shoppers with another bed size will need to check for a suitable version. Care is straightforward, with machine washing and low-heat tumble drying listed, and the warranty is limited to five years.
Pros:
- Six-sided waterproof barrier
- Fits queen mattresses from 12 to 18 inches deep
- Breathable waterproof membrane and soft polyester knit fabric
- Machine washable and tumble-dryable on low
Cons:
- This listing is for queen mattresses only
- Warranty is limited to five years
Verdict: Consider this HOSPITOLOGY encasement if you have a queen mattress that is too deep for covers capped at 15 or 16 inches.
SureGuard: A Cotton-Terry Queen Encasement
SureGuard’s queen encasement covers all six sides and fits mattresses from 13 to 16 inches deep. It is described as waterproof and bed bug proof, with a fine zipper and Invisi-Zip and SureSeal technology intended to seal the mattress. Its cotton terry top is designed to wick away moisture while retaining the feel of the mattress.
The product description lists protection against perspiration, bed wetting, liquids, stains, dust, dirt, and dander. It is also described as soft and noiseless, and it is free from vinyl, PVC, phthalates, fire retardants, and other toxic chemicals. The cover is machine washable and dryable, and the listing states that it is independently lab tested and GREENGUARD Gold certified.
This option has a narrower depth range than the HOSPITOLOGY queen encasement, but it may fit well if your mattress measures 13 to 16 inches deep. For frequent accidents and easier cleanup, the manufacturer suggests placing a fitted SureGuard Mattress Protector over the encasement. The product includes a 10-year quality guarantee.
Pros:
- Six-sided waterproof coverage with a zippered closure
- Cotton terry top designed to wick away moisture
- Fits queen mattresses from 13 to 16 inches deep
- Machine washable and dryable; 10-year quality guarantee listed
Cons:
- Depth range may not suit mattresses outside 13 to 16 inches
- The manufacturer suggests adding a separate fitted protector for frequent accidents
Verdict: Choose SureGuard if you want a cotton-terry queen encasement and your mattress fits its 13- to 16-inch depth range.
Utopia Bedding: A Waterproof King Encasement
This king-size zippered cover is made to fully encase a mattress measuring 78 by 80 inches and up to 15 inches deep. Its stretchy knitted polyester fabric is designed to fit securely without shifting, while the wrap-around zipper closes around the mattress. The waterproof layer helps block spills, sweat, drinks, and everyday accidents.
The product description calls the cover bed bug and dust mite proof, and describes the fabric as soft, durable, and non-crinkling. It can be machine washed and tumble dried on low. Those details make it a practical match for a king bed where you want enclosed coverage along with liquid protection.
Unlike the queen options above, this listing is specifically for king size. Its depth limit is 15 inches, so measure carefully if your mattress is especially thick. The supplied product details do not specify a warranty, so check the listing for current warranty information if that is important to you.
Pros:
- Full encasement with a wrap-around zipper
- Waterproof layer helps block everyday spills and accidents
- Soft, non-crinkling knitted polyester fabric
- Machine washable and suitable for low-heat tumble drying
Cons:
- Designed for king mattresses up to 15 inches deep
- Warranty details are not included in the supplied product information
Verdict: This Utopia Bedding cover is a sensible choice if you need a king-size zippered encasement and your mattress is no deeper than 15 inches.
How to Choose an Allergy Cover for Your Mattress
Decide Between a Fitted Protector and an Encasement
A fitted protector covers the sleeping surface and fits around the mattress like a sheet. A zippered encasement surrounds the mattress on all sides. If enclosing the mattress is a priority, look for a product specifically described as a zippered or six-sided encasement. The AllerEase Ultimate is listed as a fitted protector, while the other options here are zippered covers.
Measure Mattress Length, Width, and Depth
Match the cover to your mattress size and measure its depth from the bottom to the top of the sleeping surface. Include any pillow top or added layer that changes the overall thickness. Fit limits vary: for example, the queen AllerEase Maximum is listed for depths up to 15 inches, HOSPITOLOGY fits queen mattresses from 12 to 18 inches, and SureGuard fits queen mattresses from 13 to 16 inches. A cover that is too shallow may not close or fit as intended.
Choose the Protection You Need
Some covers in this list combine allergy-focused features with waterproof barriers. If spills, sweat, or accidents are a concern, check that the specific product description states it is waterproof. For broader enclosure, compare whether the product provides coverage on all six sides. Avoid assuming that a fitted protector and a zippered encasement offer the same kind of coverage.
Consider the Surface Fabric and Feel
The listed materials and design details differ. AllerEase Ultimate has a cotton top and temperature-balancing fabric technology; SureGuard has a cotton terry top; HOSPITOLOGY uses polyester knit fabric; and Utopia Bedding describes its fabric as soft and non-crinkling. Think about the surface you prefer, and read the product details carefully if sound, warmth, or moisture feel matters to you.
Check Washing and Drying Instructions
Washability is useful for a cover that needs regular cleaning, but care instructions vary. Several options are machine washable and specify low-heat tumble drying. AllerEase Maximum calls for the lowest dryer setting and says to remove the cover when dry. Following the product’s care directions can help you avoid damaging its materials or waterproof layer.
Compare Warranty Details
Warranty terms are not the same across these picks. AllerEase Maximum lists a lifetime warranty, AllerEase Ultimate lists a limited lifetime warranty, HOSPITOLOGY lists a five-year limited manufacturer’s warranty, and SureGuard lists a 10-year quality guarantee. The supplied details for Utopia Bedding do not include a warranty. Review the full product terms before making a decision, since coverage can have conditions.
Frequently Asked Questions
What is the difference between a mattress protector and an encasement?
A fitted mattress protector sits over the mattress like a fitted sheet. An encasement wraps around the mattress and closes with a zipper. If you want the mattress enclosed on every side, choose a product explicitly described as a zippered or six-sided encasement.
Does a waterproof cover also provide allergy protection?
Waterproofing and allergy-related protection are different features. Some products in this list describe both, but waterproofing alone does not indicate how a cover handles household particles. Check the product description for the specific protection claims and construction details.
How do I know whether a cover will fit my mattress?
Confirm the listed mattress size and measure the mattress depth before ordering. Pay special attention to the maximum depth, since a cover may fit one queen or king mattress but not another with a thicker profile.
Can I wash a zippered mattress encasement?
The products in this roundup list machine washing, but drying directions vary. Follow the care instructions for your specific cover. Some products call for low-heat tumble drying, while the AllerEase Maximum instructions specify the lowest setting and removing it when dry.
Should I choose a cotton top or a polyester cover?
That depends on your preferred surface and the features you value. AllerEase Ultimate and SureGuard list cotton-top materials, while HOSPITOLOGY and Utopia Bedding describe polyester-knit fabrics. Compare the stated feel, temperature, and care details rather than assuming one material is best for everyone.
Will an allergy cover stop allergy symptoms?
A mattress cover is a bedding product, not a medical treatment. The products describe barriers intended to limit certain substances from reaching or collecting in the mattress, but individual results can vary. For persistent or serious allergy concerns, ask a health professional for guidance.
Conclusion
For a zippered waterproof option with a lifetime warranty listed, the AllerEase Maximum is a well-rounded pick if its depth limits match your mattress. If your queen mattress is deeper than most, the HOSPITOLOGY encasement has the broadest stated queen depth range in this group. For a cotton-top fitted style, consider AllerEase Ultimate; for a king bed, compare Utopia Bedding with your mattress measurements. The best choice is the one that matches your preferred cover style, protection needs, and exact mattress dimensions.