A zippered mattress cover can help keep dust-mite allergens and other household particles from settling into your mattress, while also adding a layer of protection from spills. The best choice depends on whether you want a fully enclosed cover, a removable top for easier washing, or a particular mattress size and depth. These five options include waterproof designs, allergy-focused fabrics, and different fits, so check your mattress measurements before you choose.
Quick Comparison
| Product | Type | Key features | Best for |
|---|---|---|---|
| AllerEase Maximum Waterproof Zippered Protector | Full zippered encasement | Waterproof, hot-water washable, fits queen mattresses up to 15 inches deep | Everyday spill and allergen protection |
| AllerEase Platinum Zip-Off Top Protector | Removable zip-off top | Waterproof top, temperature-balancing technology, anchor bands | More convenient top-layer washing |
| AllerEase Ultimate Allergy Protection Protector | Zippered protector | Waterproof, temperature-balancing fabric, FlexFit design | Shoppers seeking an allergy-focused, snug fit |
| Guardmax Queen Zippered Mattress Protector | Six-sided encasement | Waterproof barrier, jersey-knit surface, fits up to 13 inches deep | Queen mattresses and sealed all-around coverage |
| Guardmax Full Zippered Mattress Protector | Six-sided encasement | Waterproof barrier, jersey-knit surface, fits up to 13 inches deep | Full mattresses and dust-mite barrier coverage |
Our Picks: Best Anti Allergy Mattress Cover With Zip reviews
1. AllerEase Maximum: Waterproof Protection for Everyday Use
The AllerEase Maximum is a zippered mattress encasement designed to cover the mattress and help shield it from household allergens and moisture. Its soft polyester top has a waterproof backing, making it useful if you want allergy protection along with a barrier against spills and stains.
The queen size is listed to fit mattresses up to 15 inches deep. The cover is machine washable, with care instructions calling for a hot wash when needed, nonchlorine bleach, and a separate tumble dry on the lowest setting. The manufacturer also lists a lifetime warranty, though it is wise to check the current warranty terms before buying.
Some owners describe the fabric as substantial and durable, and report that installation was manageable on their own. Still, fully enclosing a mattress can take more effort than fitting a standard fitted-sheet-style protector. Measure your mattress depth first, and take care not to tug hard on the zipper while fitting the cover.
Compared with the zip-off-top AllerEase option below, this model gives you a more conventional enclosed design rather than a removable top panel. It is a practical choice if you want waterproof coverage across the mattress and a washable encasement without extra parts.
Pros:
- Waterproof backing helps protect against spills and stains
- Queen size fits mattresses up to 15 inches deep
- Machine washable with hot-water care instructions
- Encloses the mattress with a zipper
Cons:
- Putting on a full encasement may take more work than fitting a regular protector
- Low-heat drying instructions require care to avoid damaging the cover
Verdict: Choose the AllerEase Maximum if you want a waterproof, washable zippered encasement for a queen mattress up to 15 inches deep.
2. AllerEase Platinum: Convenient Zip-Off Top for Easier Washing
The AllerEase Platinum is designed around a removable top panel. A 360-degree zipper lets you take the plush circular-knit top off for washing, while anchor bands are intended to keep the rest of the encasement in place. That setup can be useful if you want to clean the sleeping surface without removing the entire cover from the mattress.
The top has a waterproof backing, and the product description also lists temperature-balancing technology intended to wick moisture and help with comfort. The queen size fits mattresses up to 15 inches deep. Care instructions call for machine washing and separate tumble drying on the lowest setting; the listing advises against ironing.
This design is not the same as a simple fitted pad: it uses a zip-off component and anchor bands, so there are more parts to handle than with a standard encasement. The removable top is its main advantage, but it may not matter much if you are comfortable washing a full protector as needed.
Compared with the AllerEase Maximum, the Platinum puts more emphasis on washing convenience and its removable top. Consider it if you expect to clean the upper surface often and want the mattress-side portion to stay in place between washes.
Pros:
- Removable top panel can be washed separately
- Waterproof backing helps protect the mattress from spills
- Anchor bands are designed to keep the base in place when the top is removed
- Queen size fits mattresses up to 15 inches deep
Cons:
- The zip-off design has more components than a basic encasement
- The listing describes the cover as water resistant in its specifications, so confirm the protection details that matter to you
Verdict: The Platinum is a strong option if a removable, washable top is more important to you than having the simplest possible cover design.
3. AllerEase Ultimate: Allergy-Focused Coverage with a Snug Fit
The AllerEase Ultimate is a queen-size zippered protector made for shoppers who want an allergy-focused barrier with waterproof coverage. Its tightly woven fabric is designed to help prevent household particles from collecting in the mattress. The brand also describes the fabric as allergist recommended; this should be understood as a product feature, not a promise to treat allergies.
The protector includes a waterproof design and temperature-balancing fabric technology intended to retain warmth when you are cold and release it when you are hot. AllerEase’s FlexFit feature is designed to create a snug fit. Together, these details make it a comfort-focused alternative to a basic waterproof encasement.
It is machine washable, and the product data lists a limited lifetime warranty. The supplied information does not specify a maximum mattress depth for this model, so check the current size details before ordering if your mattress is especially deep.
Compared with the Maximum model, the Ultimate highlights its fabric technology and fit rather than a stated 15-inch depth limit. It may suit you if you want allergy-focused coverage and temperature-balancing features, but the Maximum offers clearer depth guidance for queen mattresses.
Pros:
- Designed to help block household particles from collecting in the mattress
- Waterproof construction helps guard against liquid spills
- Temperature-balancing fabric technology is intended to support comfort
- Machine washable and designed for a snug fit
Cons:
- The supplied product details do not state a maximum mattress depth
- It does not have the Platinum’s removable top panel
Verdict: Pick the AllerEase Ultimate if you value allergy-focused fabric and temperature-balancing features, and confirm the fit for your mattress before purchase.
4. Guardmax Queen: Six-Sided Coverage in Soft Jersey Knit
The Guardmax Queen is a fully enclosed cover with protection on all six sides. Its zipper travels around three sides and has a stitched guard flap, designed to close the area around the zipper. The product is described as a barrier for dust-mite allergens and bed bugs, as well as a waterproof layer for spills and wet nights.
The surface is jersey-knit polyester, which the manufacturer describes as soft and quiet. It fits a queen mattress measuring 60 by 80 inches and up to 12 inches deep, with stretch room up to 13 inches. The cover is also described as machine washable, but check the care instructions on the specific listing before washing.
Some owners describe the material as comfortable and not overly stiff, and report that fitting it was manageable. Even so, a zippered encasement covers the whole mattress, so you will need enough room to work around the bed during installation.
Compared with the AllerEase queen options, Guardmax offers clearly stated queen dimensions and a six-sided design. The AllerEase Maximum gives a larger stated maximum depth, while Guardmax emphasizes a sealed zipper area and a jersey-knit surface.
Pros:
- Six-sided encasement with a zipper guard flap
- Waterproof layer helps protect against spills and wet nights
- Soft jersey-knit surface is designed to be quiet
- Queen dimensions and mattress depth limits are clearly stated
Cons:
- Fits mattresses up to 13 inches deep, which is less than the stated limit for some AllerEase queen models
- Full encasement installation can take more effort than fitting a top-only protector
Verdict: Choose the Guardmax Queen if you want a fully enclosed, waterproof cover with a soft knit surface and your mattress is no deeper than 13 inches.
5. Guardmax Full: Zippered Protection for Full-Size Mattresses
This Guardmax model brings the same six-sided encasement design to a full mattress. It is made to cover a 54-by-75-inch mattress, with a stated depth of 12 inches and stretch room up to 13 inches. The zipper has a stitched guard flap, and the cover is designed to help keep dust-mite allergens and bed bugs contained while helping protect against liquid spills.
The jersey-knit polyester face is intended to feel softer and quieter than a stiff plastic-style surface. The product details describe the cover as waterproof and washable, though the listed care information for this full-size model says hand wash only. Follow the care label for the exact item you receive.
Some owners describe it as straightforward to fit and sturdy, including on foam mattresses. That can be helpful when installing an encasement alone, but mattress weight and room around the bed will affect how easy the job feels. Measure both the mattress footprint and its depth before ordering.
Unlike the Guardmax Queen, this version is sized for a full bed. Its depth limit is also lower than the stated 15-inch fit of the AllerEase Maximum queen model, so it is important to compare the exact measurements rather than choosing by brand alone.
Pros:
- Six-sided coverage with a guarded zipper closure
- Waterproof layer helps shield the mattress from spills
- Jersey-knit surface is designed to be soft and quiet
- Fits standard full dimensions and mattresses up to 13 inches deep
Cons:
- Listed care instructions say hand wash only
- May not fit a full mattress deeper than 13 inches
Verdict: The Guardmax Full is a useful pick for a full-size bed if its measurements match your mattress and you are comfortable following its hand-wash care instructions.
How to Choose a Zippered Anti-Allergy Mattress Cover
Choose the Right Type of Coverage
A fully enclosed encasement wraps around the mattress, including its sides and bottom. This design is useful if you want to cover the entire mattress, not just the sleeping surface. A removable-top design, like the AllerEase Platinum, lets you take off the upper panel while leaving the rest of the protector in place. Think about whether easy top-layer washing or all-around coverage matters more to you.
Measure Mattress Size and Depth
Check the mattress length, width, and depth before ordering. A cover that is too small can be difficult to zip closed, while excess fabric may shift or bunch. The products here have different fit limits: the AllerEase Maximum and Platinum queen models list a depth limit of 15 inches, while the Guardmax queen and full models fit mattresses up to 13 inches deep. Confirm the current size information for the exact option you plan to buy.
Decide Whether You Need Waterproof Protection
Waterproof backing can help protect a mattress from spills, sweat, and nighttime accidents. All five products in this guide are described as waterproof or as having waterproof protection, although the Platinum listing also uses “water resistant” in its specifications. If liquid protection is a priority, read the listing details carefully and follow the care instructions to help maintain the protective layer.
Consider the Fabric and Sleep Comfort
The covers use polyester-based fabrics, including jersey knit and circular knit. A soft, quiet surface may matter if you are sensitive to rustling or want the cover to feel less noticeable beneath your sheets. Temperature-balancing features are listed for some AllerEase models, but comfort is personal. Check the product construction and choose the features that best match your preferences.
Check Washing and Drying Instructions
Regular washing can be an important part of keeping bedding fresh, but care requirements differ. Some models are described as machine washable, while the Guardmax full-size listing specifies hand washing. The AllerEase products include low-heat drying instructions. Read the instructions for the exact size you select and avoid using care methods that could damage the fabric or waterproof backing.
Look at the Zipper Design
A zipper is central to a mattress encasement’s coverage, so consider how it closes and whether the design suits your needs. Guardmax describes a zipper that goes around three sides and tucks under a stitched guard flap. The AllerEase Platinum instead uses a 360-degree zipper to remove its top panel. Follow the installation directions and avoid forcing a zipper if the fabric is caught or stretched.
Keep Allergy Claims in Perspective
A zippered cover can act as a barrier between the mattress and household particles, but it is not a medical treatment and does not remove allergens already present elsewhere in a room. If allergies affect your sleep, consider the mattress cover as one part of your bedding routine and ask a healthcare professional for advice about symptoms or treatment.
Frequently Asked Questions
Does a zippered mattress cover help with dust-mite allergens?
A tightly woven, fully enclosed cover is designed to help limit the movement of dust-mite allergens from the mattress into your bedding. It cannot remove allergens from the rest of the room, and results depend on how well the cover fits and stays closed.
Is a mattress encasement the same as a fitted mattress protector?
No. A fitted protector usually covers the top and sides, while an encasement wraps around the mattress and closes with a zipper. The products in this guide use zippered designs, though the AllerEase Platinum has a removable top panel.
Will these covers fit a deep mattress?
It depends on the model. The AllerEase Maximum and Platinum queen versions list a fit for mattresses up to 15 inches deep. The Guardmax queen and full models list a maximum of 13 inches. The supplied information does not state a maximum depth for the AllerEase Ultimate, so check its current listing before buying.
Are these mattress covers waterproof?
The product descriptions identify waterproof protection for all five options. The AllerEase Platinum specifications also describe the cover as water resistant. Check the exact product details if you need a particular level of liquid protection.
Can I wash a zippered mattress cover in a washing machine?
Care instructions vary by product. Several models are described as machine washable, but the Guardmax full-size listing says hand wash only. Follow the care label for your specific cover, especially for drying, since high heat may damage some protectors.
Which option is easiest to wash?
The AllerEase Platinum is designed with a removable zip-off top that can be washed separately while anchor bands hold the rest in place. If you prefer washing a full cover at once, consider one of the standard encasements and confirm its care instructions.
Do these covers treat allergies?
No. They are designed to provide a barrier against household particles, but they are not medical products or a substitute for professional advice. If you have ongoing allergy symptoms, consult a healthcare professional.
Final Recommendation
For a queen mattress and a straightforward combination of zippered coverage, waterproof protection, and clear depth guidance, the AllerEase Maximum is the most balanced choice in this group. Choose the AllerEase Platinum if you value a removable top for washing, the AllerEase Ultimate if its allergy-focused fabric and temperature-balancing features appeal to you, or a Guardmax model if you want its six-sided design in queen or full size. Before ordering any of them, measure your mattress and check the exact care instructions.
